Anthony Davis tallied 13 points and 11 rebounds, Kyle Kuzma had 17 and Markieff Morris finished with 16 for the Lakers, who eliminated the Rockets in five games in the quarantine bubble in Orlando, Florida, AFP reported.
Los Angeles advanced to their first NBA final four since the Kobe Bryant-led Lakers beat Phoenix for the conference title and then defeated Boston for the 2010 NBA championship, the last time they won.
"It's the reason I wanted to be a part of this franchise, to take them back to a place they were accustomed to being. And that's competing for a championship," said James.
"It's an honor for me to wear the purple and gold and for us to just try to continue the legacy and just play great basketball for our fans."
This will be James's 11th career conference finals but when asked by reporters how it feels, he changed the subject to talk about the group as a whole.
"Every game is a learning experience for us. Every game is another opportunity for us to get better. We want to continue to build," said James.
The Lakers got off to their best start of the series, dominating the opening plays to take a 35-20 lead at the end of the first quarter.
Their only lull of the game came in the start of the second quarter when Houston briefly woke from their slumber and cut the lead to seven, 38-31.
But the Lakers outscored the Rockets 33-18 in the third to take full command.
They drained 19 three-pointers and shot 52 percent from the floor.
With the game in hand, the Lakers sat three-time NBA champion James and Davis for much of the fourth quarter.
"Everything is falling into place. When I got here the goal was to win a championship and now we are eight wins away," said Davis.
Once again the James Harden-led Rockets put up little resistance as Houston, after surprising the Lakers in game one of the series, lost their fourth straight and their third in a row by more than 10 points.
Harden led the Rockets with 30 points and Russell Westbrook scored just 10 in the loss.
Harden had a disappointing series, delivering another series of fourth-quarter playoff disappearing acts that have pockmarked his career.
"Tough season for us. Obviously it didn't end the way we wanted it to. So, we just got to figure it out," he said.