"The Zionist regime (Israel) is well aware that the era of hit and run is over, and therefore they are very cautious," Foreign Ministry spokesman Saeed Khatibzadeh told a virtual weekly news conference.
Iran denies having troops in Syria and says it has sent personnel to the country as military advisers. The Islamic Republic insists it will provide military advisers to Syria for as long as necessary.
"Iran's presence in Syria is advisory and naturally if anyone disrupts this advisory presence, our response will be a crushing one," Khatibzadeh said.
However, Tel Aviv’s aggressive attitude is “irremediable” and can only be confronted with comprehensive resistance on every front where it seeks to create disturbances, he added.
The so-called Syrian Observatory for Human Rightsclaimed at least 10 people, including five Iranians from the Islamic Revolution Guards Corps were killed in an Israeli attack on Damascus international airport on Wednesday.
"I do not confirm the martyrdom of Iranian forces in Syria," "Khatibzadeh said.
The Islamic Republic was the first country to rush to Syria’s assistance after the nation came under the scourge of the terrorist group of Daesh in 2014.
Elsewhere in his remarks, the spokesman said the "crimes" committed by the United States against Iran do not prevent "carefully considered" exchanges from taking place.
"The future of relations between Iran and the United States is not simple," Khatibzadeh said.
"The United States has committed repeated crimes against the Iranian people," added the official, citing a long list.
They included Washington's support for Baghdad during the 1980-1988 Iran-Iraq war, the "series of sanctions" against Tehran, and the US drone strike that assassinated top Iranian General QassemSoleimani in January.
"It is natural that (between two) members of the United Nations (like the US and Iran) there have always been, and there are, very carefully considered exchanges, in a known framework," Khatibzadeh said, while noting that it "does not mean that Iran is forgetting this list of crimes."
Tehran and Washington, enemies for more than four decades, have edged to the brink of a military encounter twice since June 2019, amid tensions that escalated after outgoing US President Donald Trump unilaterally withdrew from Iran's 2015 nuclear agreement with world powers.
US president-elect Joe Biden has promised a return to diplomacy with Iran after four hawkish years under Trump.
‘Arab betrayal boosting US pro-Israel work’
Separately, Khatibzadeh commented on Mike Pompeo’s recent visit to the occupied territories, his last in his capacity as the US secretary of state, and the remarks that he made during the visit.
During the visit, Pompeo boasted about the Trump administration’s brokering of “peace deals” between Tel Aviv and regional Arab states and alleged that the raft of “normalization” deals had led to “isolation” of Iran.
Khatibzadeh regretted the “treachery” of the Arab regimes – the United Arab Emirates, Bahrain, and Sudan – in their entering the détente with Tel Aviv.
Without their betrayal, he said, Pompeo would not have been able to go about “whitewashing inhumane Israeli action” today.
“Those who created such [enabling] atmosphere for the US should be held accountable,” the spokesman said, calling the betrayal and the White House’s unabashed defense of Israel “two sides of the same coin.”
The spokesperson said the Arab states were no more than a handful of “notorious” regimes that were isolated even among their own peoples, calling it unlikely that they could draw much benefit from endearing themselves to the US and Israel.
US anti-Yemen bid
Khatibzadeh, meanwhile, referred to reports about the United States’ potential designation of Yemen’s HouthiAnsarullah movement as a “terrorist organization.”
The popular defense group has been fending for Yemen since 2015, when Saudi Arabia and its allies started a US-backed invasion of the impoverished country. The invasion has killed tens of thousands of Yemenis and turned the entire country into the scene of the world’s “worse humanitarian crisis.”
Observers say such designation that has already been received warmly by Saudi Arabia’s rulers could hugely embolden Riyadh in its atrocities in Yemen.
Khatibzadeh said the Saudi regime’s support for the blacklisting “comes as no surprise” as Riyadh has been stonewalling efforts aimed at ending Yemen’s crisis.
He cited some instances of the kingdom’s atrocities against the Arab world’s poorest nation such as the use of cluster bombs against civilians and bombarding some areas of Yemen on more than 17 occasions.
The Islamic Republic, however, considers respect for the Yemeni people’s demands, intra-Yemeni negotiation and adherence to standing international conflict-resolution mechanisms as the only viable solution for the crisis, Khatibzadeh stated.
Reuters, AFP and Press TV contributed to this story.