Ayatollah Khamenei made the remarks during a meeting of the Supreme Council for Economic Coordination among the three branches of power in Iran.
The Leader said Iranians have been subjected to such a crime for many years, but that the sanctions have intensified over the past three years under the current US administration, Press TV reported.
He said there are two ways to end the restrictions, either by “neutralizing the sanctions and overcoming them” or having “the bans removed.”
“Of course, we tried the path of [having] the sanctions lifted once and negotiated for several years [to that effect], but it produced no results,” Ayatollah Khamenei added.
Referring to the other solution, the Leader said, “This path may have difficulties at the beginning, but there will be a positive outcome.”
“We have a lot of potential and capabilities to render the sanctions ineffective, provided that we muster the will, strive and meet the challenges outright,” he said.
“If we manage to overcome the sanctions through [our own] efforts and initiatives while holding firm against the problems, the other side will gradually lift the bans since it will see their ineffectiveness,” Ayatollah Khamenei pointed out.
The Leader further urged Iranians not to rely on aid from abroad to resolve domestic problems.
He also blasted France, Britain and Germany for taking anti-Iran stances.
“The situation of the United States is far from clear and the Europeans are constantly adopting positions against Iran,” Ayatollah Khamenei said.
The Leader also slammed the European troika for its interference in the West Asia region.
“They tell us not to interfere in the region, whereas it is them who are interfering the most wrongly in the affairs of the region, with Britain and France possessing destructive nuclear missiles and Germany being on the same path. Then they tell us not to have missiles,” he said
Ayatollah Khamenei rejected the trio’s call on Iran to give up its missile program, saying the issue “is no business of” them.