"We hope that Rafael Grossi's visit will be as constructive as the previous ones," Foreign Ministry spokesman Saeed Khatibzadeh told reporters.
The spokesman made the comments before the scheduled arrival of Grossi, the head of the International Atomic Energy Agency, in Tehran on Monday.
Grossi is expected to meet Foreign Minister Hossein Amir-Abdollahian and Atomic Energy Organization of Iran’s chief Mohammad Eslami, who is also one of Iran's vice presidents, AFP wrote.
"We have always advised the IAEA to stay on the path of technical cooperation, and to not let certain countries pursue their political orientations on behalf of the IAEA," Khatibzadeh added.
In a tweet on Monday before arriving in Tehran, Grossi hoped to “establish a fruitful and cooperative channel of direct dialogue so the IAEA can resume essential verification activities in the country”.
The IAEA chief was last in Tehran on September 12, when he clinched a deal on access to monitoring equipment at some Iranian nuclear facilities.
Russia’s chief negotiator at the Vienna talks Mikhail Ulyanov called Grossi's trip to Tehran a “good opportunity” for the agency and Iran to “establish closer contacts and cooperation on issues of common interest.”
“We wish the two sides to have productive discussions,” Ulyanov tweeted on Sunday.
Grossi's visit comes as Iran readies for talks with world powers in Vienna on November 29 on restoring the nuclear deal, known as the JCPOA, with major powers, that promised it sanctions relief in return for curbs on its nuclear program.
"We will leave for Vienna with a full team and a serious will to lift the sanctions," Khatibzadeh said.
"The other parties should also try to come to Vienna to reach a practical and comprehensive agreement."
The landmark deal was torpedoed in 2018 when former US president Donald Trump unilaterally withdrew Washington from it and imposed a harsh sanctions regime.
The remaining parties to the deal – Britain, China, France, Germany and Russia – known as the P4+1, will join the talks while the United States will participate indirectly.
Khatibzadeh stressed that Washington need to provide guarantees that it would not once again ditch the JCPOA, according to Press TV.
“It is natural that both we and the P4+1 need genuine guarantees, and it is better for the American officials who would come to Vienna to know that [they need to] give these guarantees,” he said.